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    <p>To install this package, start R and enter:</p>
<pre>## try http:// if https:// URLs are not supported
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    <p> In most cases, you don't need to download the
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        <h1>nethet</h1>




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    <p>This package is for version 3.4 of Bioconductor;
for the stable, up-to-date release version, see
<a href="/packages/nethet/">nethet</a>.</p>


    

    <h2>A bioconductor package for high-dimensional exploration of biological network heterogeneity</h2>

    <p>
        Bioconductor version: 3.4
    </p>

    <p>Package nethet is an implementation of statistical solid methodology enabling the analysis of network heterogeneity from high-dimensional data. It combines several implementations of recent statistical innovations useful for estimation and comparison of networks in a heterogeneous, high-dimensional setting. In particular, we provide code for formal two-sample testing in Gaussian graphical models (differential network and GGM-GSA; Stadler and Mukherjee, 2013, 2014) and make a novel network-based clustering algorithm available (mixed graphical lasso, Stadler and Mukherjee, 2013).</p>

    <p>Author: Nicolas Staedler, Frank Dondelinger </p>

    <p>Maintainer: Nicolas Staedler &#x3c;&#x73;&#x74;&#x61;&#x65;&#x64;&#x6c;&#x65;&#x72;&#x2e;&#x6e;&#x20;&#x61;&#x74;&#x20;&#x67;&#x6d;&#x61;&#x69;&#x6c;&#x2e;&#x63;&#x6f;&#x6d;&#x3e;, Frank Dondelinger &#x3c;&#x66;&#x64;&#x6f;&#x6e;&#x64;&#x65;&#x6c;&#x69;&#x6e;&#x67;&#x65;&#x72;&#x2e;&#x77;&#x6f;&#x72;&#x6b;&#x20;&#x61;&#x74;&#x20;&#x67;&#x6d;&#x61;&#x69;&#x6c;&#x2e;&#x63;&#x6f;&#x6d;&#x3e; </p>



    <div id="bioc_citation_outer">
    <p>Citation (from within R,
      enter <code>citation("nethet")</code>):</p>
      <div id="bioc_citation" class="bioc_citation"></div>
    </div>

    <h3>Installation</h3>

    <p>To install this package, start R and enter:</p>


    <pre>## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("nethet")</pre>


    <h3>Documentation</h3>



<p>To view documentation for the version of this package installed
    in your system, start R and enter:
</p>
<pre>browseVignettes("nethet")</pre>
    <p>&nbsp;</p>



    <table>
        
        
        
            
                
                
                <tr class="row_odd">
                    <td class="docFixedWidth">
                        
                        <a onClick="javascript: pageTracker._trackPageview('../vignettes/nethet/inst/doc/nethet.pdf'); " href="../vignettes/nethet/inst/doc/nethet.pdf">PDF</a>
                        
                    </td>
                    <td class="docFixedWidth">
                        
                        <a onClick="javascript: pageTracker._trackPageview('../vignettes/nethet/inst/doc/nethet.R'); " href="../vignettes/nethet/inst/doc/nethet.R">R Script</a>
                        
                    </td>
                    <td>nethet</td>
                </tr>

            
        


            
            <tr class="row_even">
                <td class="docFixedWidth">
                    <a onClick="javascript: pageTracker._trackPageview('../manuals/nethet/man/nethet.pdf'); " href="../manuals/nethet/man/nethet.pdf">PDF</a>
                </td>
                <td class="docFixedWidth">&nbsp;</td>
                <td>Reference Manual</td>
                
            </tr>


            


            
                
                <tr class="row_odd">
                    <td class="docFixedWidth">
                        <a href="../news/nethet/NEWS">Text</a>
                    </td>
                    <td class="docFixedWidth">&nbsp;</td>
                    <td>NEWS</td>
                </tr>
                
            


            


            

            




    </table>



    <h3>Details</h3>
    
    <table class="details">
        <tr class="row_odd">
            <td>biocViews</td>
            <td><a href="../../BiocViews.html#___Clustering">Clustering</a>, <a href="../../BiocViews.html#___GraphAndNetwork">GraphAndNetwork</a>, <a href="../../BiocViews.html#___Software">Software</a></td>
        </tr>

        <tr class="row_even">
            <td>Version</td>
            <td>1.6.0</td>
        </tr>

        
            <tr id="since" class="row_odd">
                <td>In Bioconductor since</td>
                <td>BioC 3.1 (R-3.2) (2 years)</td>
            </tr>
        



        <tr class="row_even">
            <td>License</td>
            <td>GPL-2</td>
        </tr>

        <tr class="row_odd">
            <td>Depends</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Imports</td>
            <td><a class="cran_package" href="http://cran.rstudio.com/web/packages/glasso/index.html">glasso</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/mvtnorm/index.html">mvtnorm</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/parcor/index.html">parcor</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/GeneNet/index.html">GeneNet</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/huge/index.html">huge</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/CompQuadForm/index.html">CompQuadForm</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/ggm/index.html">ggm</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/mclust/index.html">mclust</a>, parallel, <a class="cran_package" href="http://cran.rstudio.com/web/packages/GSA/index.html">GSA</a>, <a href="../../bioc/html/limma.html">limma</a>, <a href="../../bioc/html/multtest.html">multtest</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/ICSNP/index.html">ICSNP</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/glmnet/index.html">glmnet</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/network/index.html">network</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/ggplot2/index.html">ggplot2</a></td>
        </tr>

        <tr class="row_odd">
            <td>LinkingTo</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Suggests</td>
            <td><a class="cran_package" href="http://cran.rstudio.com/web/packages/knitr/index.html">knitr</a>, <a class="cran_package" href="http://cran.rstudio.com/web/packages/xtable/index.html">xtable</a>, <a href="../../bioc/html/BiocStyle.html">BiocStyle</a></td>
        </tr>

        <tr class="row_odd">
            <td>SystemRequirements</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Enhances</td>
            <td></td>
        </tr>

        <tr class="row_odd">
            <td>URL</td>
            <td><a href=""></a> </td>
        </tr>

        

        <tr class="row_even">
            <td>Depends On Me</td>
            <td></td>
        </tr>

        <tr class="row_odd">
            <td>Imports Me</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Suggests Me</td>
            <td></td>
        </tr>

        
            <tr class="row_odd">
                <td><a href="http://bioconductor.org/checkResults/3.4/bioc-LATEST/nethet/">Build Report</a></td>
                <td>&nbsp;</td>
            </tr>
        


    </table>

    <h3 id="archives">Package Archives</h3>

    <p>Follow <a href="/install/#install-bioconductor-packages">
    Installation</a> instructions to use this
    package in your R session.</p>

    

    <table>
        <tr class="row_odd">
            <td>Package Source</td>
            <td class="rpack"><a onClick="javascript: pageTracker._trackPageview('../src/contrib/nethet_1.6.0.tar.gz'); " href="../src/contrib/nethet_1.6.0.tar.gz">
                nethet_1.6.0.tar.gz</a></td>
            </tr>

            <tr class="row_even">
                <td>Windows Binary</td>
                <td class="rpack">
                    
                    
                    <a onClick="javascript: pageTracker._trackPageview('../bin/windows/contrib/3.3/nethet_1.6.0.zip'); " href="../bin/windows/contrib/3.3/nethet_1.6.0.zip">
                        nethet_1.6.0.zip</a> (32- &amp; 64-bit)
                    
                    </td>
                </tr>


                


                    <tr class="row_odd">
                        <td>Mac OS X 10.9 (Mavericks)</td>
                        <td class="rpack"><a onClick="javascript: pageTracker._trackPageview('../bin/macosx/mavericks/contrib/3.3/nethet_1.6.0.tgz'); " href="../bin/macosx/mavericks/contrib/3.3/nethet_1.6.0.tgz">
                            nethet_1.6.0.tgz</td>
                    </tr>


                


                
                    <tr class="row_even">
                        <td id="svn_source">Subversion source</td>
                        <td><a href="https://hedgehog.fhcrc.org/bioconductor/branches/RELEASE_3_4/madman/Rpacks/nethet/">(username/password: readonly)</a></td>
                    </tr>
                

                
                    <tr class="row_odd">
                        <td id="github_source">Git source</td>
                        <td><a href="https://github.com/Bioconductor-mirror/nethet/tree/release-3.4">https://github.com/Bioconductor-mirror/nethet/tree/release-3.4</a></td>
                    </tr>
                


                    <tr class="row_even">
                        <td>Package Short Url</td>
                        <td><a title="Canonical url for use in publications, etc., will always redirect to current release version (or devel if package is not in release yet)." href="/packages/nethet/">http://bioconductor.org/packages/nethet/</a></td>
                    </tr>


                    <tr class="row_odd">
                        <td>Package Downloads Report</td>
                        <td><a href="http://bioconductor.org/packages/stats/bioc/nethet/">Download Stats</a></td>
                    </tr>

                </table>




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