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  <meta property="og:description" content="The HOPACH clustering algorithm builds a hierarchical tree of clusters by recursively partitioning a data set, while ordering and possibly collapsing clusters at each level. The algorithm uses the Mean/Median Split Silhouette (MSS) criteria to identify the level of the tree with maximally homogeneous clusters. It also runs the tree down to produce a final ordered list of the elements. The non-parametric bootstrap allows one to estimate the probability that each element belongs to each cluster (fuzzy clustering)." />
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    <p>To install this package, start R and enter:</p>
<pre>## try http:// if https:// URLs are not supported
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biocLite("hopach")</pre>
    <p> In most cases, you don't need to download the
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        <h1>hopach</h1>




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    <p>This package is for version 3.4 of Bioconductor;
for the stable, up-to-date release version, see
<a href="/packages/hopach/">hopach</a>.</p>


    

    <h2>Hierarchical Ordered Partitioning and Collapsing Hybrid (HOPACH)</h2>

    <p>
        Bioconductor version: 3.4
    </p>

    <p>The HOPACH clustering algorithm builds a hierarchical tree of clusters by recursively partitioning a data set, while ordering and possibly collapsing clusters at each level. The algorithm uses the Mean/Median Split Silhouette (MSS) criteria to identify the level of the tree with maximally homogeneous clusters. It also runs the tree down to produce a final ordered list of the elements. The non-parametric bootstrap allows one to estimate the probability that each element belongs to each cluster (fuzzy clustering).</p>

    <p>Author: Katherine S. Pollard, with Mark J. van der Laan &#x3c;&#x6c;&#x61;&#x61;&#x6e;&#x20;&#x61;&#x74;&#x20;&#x73;&#x74;&#x61;&#x74;&#x2e;&#x62;&#x65;&#x72;&#x6b;&#x65;&#x6c;&#x65;&#x79;&#x2e;&#x65;&#x64;&#x75;&#x3e; and Greg Wall </p>

    <p>Maintainer: Katherine S. Pollard &#x3c;&#x6b;&#x61;&#x74;&#x68;&#x65;&#x72;&#x69;&#x6e;&#x65;&#x2e;&#x70;&#x6f;&#x6c;&#x6c;&#x61;&#x72;&#x64;&#x20;&#x61;&#x74;&#x20;&#x67;&#x6c;&#x61;&#x64;&#x73;&#x74;&#x6f;&#x6e;&#x65;&#x2e;&#x75;&#x63;&#x73;&#x66;&#x2e;&#x65;&#x64;&#x75;&#x3e; </p>



    <div id="bioc_citation_outer">
    <p>Citation (from within R,
      enter <code>citation("hopach")</code>):</p>
      <div id="bioc_citation" class="bioc_citation"></div>
    </div>

    <h3>Installation</h3>

    <p>To install this package, start R and enter:</p>


    <pre>## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("hopach")</pre>


    <h3>Documentation</h3>



<p>To view documentation for the version of this package installed
    in your system, start R and enter:
</p>
<pre>browseVignettes("hopach")</pre>
    <p>&nbsp;</p>



    <table>
        
        
        
            
                
                
                <tr class="row_odd">
                    <td class="docFixedWidth">
                        
                        <a onClick="javascript: pageTracker._trackPageview('../vignettes/hopach/inst/doc/hopach.pdf'); " href="../vignettes/hopach/inst/doc/hopach.pdf">PDF</a>
                        
                    </td>
                    <td class="docFixedWidth">
                        
                        <a onClick="javascript: pageTracker._trackPageview('../vignettes/hopach/inst/doc/hopach.R'); " href="../vignettes/hopach/inst/doc/hopach.R">R Script</a>
                        
                    </td>
                    <td>hopach</td>
                </tr>

            
        


            
            <tr class="row_even">
                <td class="docFixedWidth">
                    <a onClick="javascript: pageTracker._trackPageview('../manuals/hopach/man/hopach.pdf'); " href="../manuals/hopach/man/hopach.pdf">PDF</a>
                </td>
                <td class="docFixedWidth">&nbsp;</td>
                <td>Reference Manual</td>
                
            </tr>


            


            


            


            

            




    </table>



    <h3>Details</h3>
    
    <table class="details">
        <tr class="row_odd">
            <td>biocViews</td>
            <td><a href="../../BiocViews.html#___Clustering">Clustering</a>, <a href="../../BiocViews.html#___Software">Software</a></td>
        </tr>

        <tr class="row_even">
            <td>Version</td>
            <td>2.34.0</td>
        </tr>

        
            <tr id="since" class="row_odd">
                <td>In Bioconductor since</td>
                <td>BioC 1.6 (R-2.1) or earlier (&gt; 12 years)</td>
            </tr>
        



        <tr class="row_even">
            <td>License</td>
            <td>GPL (>= 2)</td>
        </tr>

        <tr class="row_odd">
            <td>Depends</td>
            <td>R (>= 2.11.0), <a class="cran_package" href="http://cran.rstudio.com/web/packages/cluster/index.html">cluster</a>, <a href="../../bioc/html/Biobase.html">Biobase</a>, methods</td>
        </tr>

        <tr class="row_even">
            <td>Imports</td>
            <td>graphics, grDevices, stats, utils, <a href="../../bioc/html/BiocGenerics.html">BiocGenerics</a></td>
        </tr>

        <tr class="row_odd">
            <td>LinkingTo</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Suggests</td>
            <td></td>
        </tr>

        <tr class="row_odd">
            <td>SystemRequirements</td>
            <td></td>
        </tr>

        <tr class="row_even">
            <td>Enhances</td>
            <td></td>
        </tr>

        <tr class="row_odd">
            <td>URL</td>
            <td><a href="http://www.stat.berkeley.edu/~laan/">http://www.stat.berkeley.edu/~laan/</a> <a href="http://docpollard.org/">http://docpollard.org/</a> </td>
        </tr>

        

        <tr class="row_even">
            <td>Depends On Me</td>
            <td></td>
        </tr>

        <tr class="row_odd">
            <td>Imports Me</td>
            <td><a href="../../bioc/html/phenoTest.html">phenoTest</a></td>
        </tr>

        <tr class="row_even">
            <td>Suggests Me</td>
            <td><a href="../../bioc/html/BiocCaseStudies.html">BiocCaseStudies</a></td>
        </tr>

        
            <tr class="row_odd">
                <td><a href="http://bioconductor.org/checkResults/3.4/bioc-LATEST/hopach/">Build Report</a></td>
                <td>&nbsp;</td>
            </tr>
        


    </table>

    <h3 id="archives">Package Archives</h3>

    <p>Follow <a href="/install/#install-bioconductor-packages">
    Installation</a> instructions to use this
    package in your R session.</p>

    

    <table>
        <tr class="row_odd">
            <td>Package Source</td>
            <td class="rpack"><a onClick="javascript: pageTracker._trackPageview('../src/contrib/hopach_2.34.0.tar.gz'); " href="../src/contrib/hopach_2.34.0.tar.gz">
                hopach_2.34.0.tar.gz</a></td>
            </tr>

            <tr class="row_even">
                <td>Windows Binary</td>
                <td class="rpack">
                    
                    
                    <a onClick="javascript: pageTracker._trackPageview('../bin/windows/contrib/3.3/hopach_2.34.0.zip'); " href="../bin/windows/contrib/3.3/hopach_2.34.0.zip">
                        hopach_2.34.0.zip</a> (32- &amp; 64-bit)
                    
                    </td>
                </tr>


                


                    <tr class="row_odd">
                        <td>Mac OS X 10.9 (Mavericks)</td>
                        <td class="rpack"><a onClick="javascript: pageTracker._trackPageview('../bin/macosx/mavericks/contrib/3.3/hopach_2.34.0.tgz'); " href="../bin/macosx/mavericks/contrib/3.3/hopach_2.34.0.tgz">
                            hopach_2.34.0.tgz</td>
                    </tr>


                


                
                    <tr class="row_even">
                        <td id="svn_source">Subversion source</td>
                        <td><a href="https://hedgehog.fhcrc.org/bioconductor/branches/RELEASE_3_4/madman/Rpacks/hopach/">(username/password: readonly)</a></td>
                    </tr>
                

                
                    <tr class="row_odd">
                        <td id="github_source">Git source</td>
                        <td><a href="https://github.com/Bioconductor-mirror/hopach/tree/release-3.4">https://github.com/Bioconductor-mirror/hopach/tree/release-3.4</a></td>
                    </tr>
                


                    <tr class="row_even">
                        <td>Package Short Url</td>
                        <td><a title="Canonical url for use in publications, etc., will always redirect to current release version (or devel if package is not in release yet)." href="/packages/hopach/">http://bioconductor.org/packages/hopach/</a></td>
                    </tr>


                    <tr class="row_odd">
                        <td>Package Downloads Report</td>
                        <td><a href="http://bioconductor.org/packages/stats/bioc/hopach/">Download Stats</a></td>
                    </tr>

                </table>




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